A new treatment

Since our last post, quite a bit has happened, but we finally have some definitive news to share. Shortly after we posted, Brad began Rituxan treatments. They were done in the cancer center, once a week, and had very few side effects beyond making him feel tired. (He even kept his beard, which has regrown since his transplant.) At the same time, his oncologist drastically reduced the amount of immune suppressant medications Brad was taking, in an effort to get his immune system back up and running so it could effectively fight the Epstein-Barr virus that was causing the new cancer. We know the immune system got right to work, because he had a new flareup of graft vs. host disease—fortunately, it was comparatively mild and came in the form of a not-too-bothersome skin rash. This has been quickly controlled with steroids, and now Brad feels relatively well.

The best feature, by far, of the past month has been that Brad’s doctor cleared him to fly (more on future destinations in a minute), and so for the week of Thanksgiving we took a family trip to Hawaii. Luckily, Brad got on the steroids right before we went, and while we were there he had comparatively good energy. A family vacation was exactly what we all needed and we got to spend a lot of time poolside and enjoying ourselves at the resort we stayed at. Brad was able to go swimming, we met up with good friends who happened to be vacationing nearby, and we took a day trip for shave ice, shrimp truck lunch, and checking out the waves on Oahu’s North Shore.

We got back last Friday and on Monday Brad had a PET scan to find out how well the treatment has been working. The news was overall positive: while he still has evidence of disease and a few lesions, the Rituxan (combined with reduced immune suppression) worked to shrink the cancer considerably. Its results were a lot better than his oncologist had initially cautioned us to expect. It feels very weird to say that a scan showing cancer is good news—but compared to how much cancer there was before, it really is. It also leaves Brad eligible for a very promising clinical trial, one his oncologist feels is his best treatment option. The trial takes place at Sloan Kettering in New York (yep, 3000 miles away) and now that we have scan results, Brad’s first appointment is next Thursday. (Let me just say, it is taking a lot of restraint not to riff on the lyrics to “New York, New York” in this post.)

So, we are now in full logistical scrambling mode to make this happen. Kate will stay home with the girls, whose primary concern is whether their dad will be home for Christmas. (It’s touch and go; the treatment lasts for 3 weeks, so we just aren’t sure if they can complete it in time for him to fly home.) Brad’s parents will go to New York to stay with him, and we are so very grateful to them for their invaluable help. For any of our readers within easy distance of New York, Brad’s treatments will be just once a week, and he will have a lot of down time and would love to see friends. If you’d like to visit, call or text Brad directly (or if you don’t have his number, please message Kate and I’ll put you in touch). We’ll update again when there is news from Manhattan.